About iovera°
iovera° is a non-surgical treatment that uses targeted cold to block pain with long lasting effects.
Common Uses of iovera°
iovera° is commonly used to reduce pain before or after orthopedic procedures and to help manage chronic conditions like:
Knee Pain
Knee pain—whether from injury, arthritis, or everyday wear and tear—can make even simple movements difficult. iovera° offers targeted relief by safely disrupting pain signals in the nerves around the knee, helping reduce discomfort during daily activities or while waiting for or recovering from surgery.
Shoulder Pain
Shoulder pain often stems from overuse, rotator cuff injuries, or arthritis, leading to limited motion and constant aching. With iovera°, patients can experience drug-free pain relief that helps improve function and comfort, especially while waiting for surgery or managing chronic shoulder issues.
Ankle Pain
Chronic ankle pain from conditions like ligament damage, arthritis, or overuse can interfere with walking and stability. iovera° precisely targets the nerves causing discomfort, providing long-lasting relief that helps patients stay mobile without the need for ongoing medication.
Hip Pain
Hip pain, whether from osteoarthritis, bursitis, or injury, often makes sitting, standing, or walking a challenge. iovera° helps interrupt the pain at its source by applying focused cold to nerves around the hip, reducing pain and improving quality of life without invasive procedures.
Sacroiliac (SI) Joint Pain
Pain in the sacroiliac (SI) joint, where the spine meets the pelvis, can cause deep, aching discomfort in the lower back and hips. iovera° provides a non-surgical way to ease SI joint pain by stopping pain signals before they reach the brain—allowing for better movement and less daily disruption.
Post-operative Joint Pain
Post-operative joint pain can delay recovery and increase reliance on medication. iovera° offers a way to manage this pain at the nerve level, helping reduce the need for opioids and supporting a smoother, more comfortable healing process after joint surgery.
The iovera° system uses N2O, which does not reach temperatures cold enough to cause irreversible nerve damage.
Cryoneurolysis is the freezing of the signal-carrying parts of a nerve.
iovera° uses focused cold therapy, also called cryoneurolysis. A small, handheld device delivers controlled cold to a targeted nerve, creating a temporary “pause” in its ability to send pain signals. The nerve remains intact and will gradually restore function over time—meaning relief without permanent damage, and without the use of drugs.
Targeted Cold is applied directly to a peripheral nerve.
iovera° uses nitrous oxide and the body’s own fluid to create a Precise Cold Zone under the skin. Cold enough to immediately prevent the nerve from sending pain signals without causing damage to the surrounding area.
The effect on the nerve is temporary, providing pain relief until the nerve regenerates and function is restored.
The iovera° treatment does not inject opioids.
Pain relief can last up to 90 Days per treatment.
Why Choose iovera°?
It’s drug-free:
iovera° delivers targeted pain relief without the need for opioids or long-term medications.
It’s fast-acting:
Most patients experience immediate relief after treatment, with results lasting several months.
It targets pain at the source:
By safely applying cold to specific peripheral nerves, iovera° temporarily stops them from sending pain signals—without damaging surrounding tissue.
What to Expect During Your iovera° Treatment
No incisions or sutures — just a small needle-sized tip applied through the skin.
You’ll be awake and comfortable during the procedure.
Relief begins immediately for most patients and continues to improve over the following days.
No downtime required — you can typically return to normal activity right after your appointment.
Take the First Step Toward Relief
If you’re living with chronic joint pain or looking for an alternative to opioids before or after surgery, iovera° might be right for you.
Schedule a consultation today and discover what drug-free, fast-acting nerve pain relief feels like.
Be your best self
be pain free
Schedule an appointment to determine if you are a good candidate for these advanced procedures.